The critical period for long-term potentiation in primary sensory cortex

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The critical period for long-term potentiation in primary sensory cortex

Long-term potentiation (LTP) is a synaptic process frequently proposed as a candidate mechanism underlying memory (Bliss and Collingridge, 1993). Under the correct conditions (which in almost all cases means during coincident activation of preand postsynaptic neurons), within a matter of seconds, the gain of synaptic transmission will increase and remain elevated for a period of hours to weeks....

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P19: Long-Term Potentiation

The term synaptic plasticity points to a series of persistent changes related to the activity of synapses. Long-term potentiation (LTP) is a reflection of synaptic plasticity that has an important role in learning and memory. LTP is a long-lasting increase of synaptic activity due to enhancement of excitatory synaptic transmission after a high-frequency train of electrical stimulations. Differe...

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Synaptic plasticity in the central nervous system (CNS) of mammals has been discussed for many years. Several forms of synaptic plasticity of mammal’s CNS have been identified, such as those that occur in long-term potentiation (LTP). Different types of LTP have been observed in distinctive areas of the CNS of mammals. The hippocampus is one of the most important areas in the CNS that pla...

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Critical periods for plasticity of thalamic sensory inputs play an important role in developing neocortical circuits. During an early postnatal time window, pyramidal cells of visual, auditory, and somatosensory cortex undergo structural refinement and possess an enhanced ability for activity-dependent synaptic plasticity. In olfactory cortex, however, pyramidal cells receive direct sensory inp...

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[All together now: long term potentiation in the human cortex].

INTRODUCTION Long term potentiation (LTP) is defined as a long-lasting enhancement in communication between two neurons after the delivery of high frequency trains of electrical stimulation. This adjustment in synaptic efficacy is the physiological process that sustains learning and memory. However, few studies have addressed the existence of a similar phenomenon in the human cortex, even thoug...

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ژورنال

عنوان ژورنال: Neuron

سال: 1995

ISSN: 0896-6273

DOI: 10.1016/0896-6273(95)90136-1